Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Breast cancer remains one of the most prevalent and life-threatening forms of cancer, impacting millions worldwide. This malignancy's heterogeneity and complexity have long posed significant ...

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

A caffeine-triggered switch that turns CRISPR gene editing on and off inside cells could one day improve cancer therapy.

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

Researchers mapped pineoblastoma tumors at single-cell resolution and found they rely on genes linked to light sensing. The same dependency appears in medulloblastoma, and retinoblastoma, offering a ...

New research links Wnt signalling to aggressive paediatric liver cancer and chemoresistance. Learn what this means for treatment.