Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...
Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of ...
Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...
Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings ...
Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called Pro-Aging Metabolic Reprogramming (PAMRP), which could change our ...
FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARĪ³, peroxisome proliferator-activated receptor ...
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