Antibody therapies work in part by binding to Fc receptors, proteins found on immune cells that control key immune functions such as antibody-mediated cell killing and inflammation. Since these ...

Because the antibodies are so selective for beta cells, the treatment appears to be safe for long-term use with few side effects, the team says. At this stage, the study has only been conducted in ...

A growing portfolio of in vivo-ready bispecific antibodies provides immediate access to anti-mouse and anti-human dual-target formats. Custom production options allow researchers to tailor constructs ...

Antibody humanization involves modifying antibodies from non-human sources, such as mice, to decrease their immunogenicity in human applications. While mouse monoclonal antibodies are specific, they ...

A study conducted in mice by researchers in the lab of Irvine Weissman, MD, at Stanford University School of Medicine, and at the National Institutes of Health’s Rocky Mountain Laboratories, has ...

Researchers have developed an antibody that prevents the activation of the Dickkopf 1-Cytoskeleton-associated protein 4 (DKK1-CKAP4) pathway, which is important for tumor growth in several cancers, ...

New active ingredients such as antibodies are usually tested individually in laboratory animals. Researchers at UZH have now developed a technology that can be used to test around 25 antibodies ...

Researchers are engineering a new class of miniature antibodies, called intrabodies, that can operate inside living cells to ...